Harvard T.H. Chan Microbiome Collection Core


Harvard Chan Microbiome Analysis Core

The HMAC provides a single point of contact for integrative microbiome informatics and analysis of data from amplicon (16S/18S rRNA gene and internal transcribed spacer DNA), and metagenomic and metatranscriptomic shotgun sequencing studies of the human microbiome as well as metabolomics analysis of the human microbiota. The Core has extensive experience with large metagenomic, metatranscriptomic, and individual microbial genome data collections, including bioinformatics processing of such data from large cohorts, quantitative ecology, and subsequent microbial systems analysis. By integrating data on microbial gene function and taxonomic profiles with host data, we enable researchers to interpret metabolic activities of uncultivable microbiota and assess its impact on the host.

BiOS Freezer Core

The BiOS Freezer Core is designed to assist in the management and storage of samples for PI eligible investigators at the Harvard Chan School. This freezer is a large capacity negative 80°C freezer with the ability to store 100,000 to 10 million samples, depending on labware size. The BiOS Freezer Core is intended to be an alternative storage option to upright and chest negative 80°C freezers, conserving costs, energy, and space, while ensuring sample integrity, access, and tracking.